Background: The evaluation of the risk factors associated with the long-term Survival rate of patients with myocardial infarction (MI) and the effects of discharge medications can significantly help select the most effective strategies for improving treatment. Study Design: A retrospective cohort study. Methods: The participants of this retrospective cohort study were 21, 181 patients who suffered from MI and were hospitalized in the cardiac care unit (CCU) of different public, private, and military hospitals in Iran from 20 March 2013 to 20 March 2014. Participants were followed up until February 2020 for any cardiovascular disease (CVD) mortality. To evaluate Survival rate, the differences between groups, and the factors related to MI death, Kaplan-Meier, log-rank test, and Cox proportional-hazards model were used, respectively. Results: One, three, five, and seven-year Survival rates of patients were 88%, 81%, 78%, and 74%, respectively. Regarding the interaction effect of prescribed medical drugs, the highest 7-year Survival rate of 86% (95% CI: 72%, 93%) was related to people who consumed anticoagulants, aspirin, clopidogrel, beta blockers, angiotensin-converting enzymes (ACEs), and angiotensin II receptor antagonist simultaneously. Considering the effect of other variables, the consumption of anticoagulants was associated with a decrease in Survival rate (HR = 1. 13 CI: 1. 06, 1. 19). Conclusion: As evidenced by the results of this study, different combinations of prescribed medication drugs had protective effects on long-term mortality compared to the group without any drug. Nonetheless, according to the drugs in each combination therapy, this protective effect ranged from HR = 0. 27 to HR = 0. 89. It is recommended that further studies compare the long-term effects of different drug combinations and also consider adherence to treatment in evaluating the effects of these combinations.

BACKGROUND: Stomach cancer is one of the most common malignancies worldwide. In Iran, the mortality of stomach cancer is the first cause of death due to cancer in both sexes. This study was designed to estimate Survival rate of stomach cancer at national level.METHODS: From the national cancer registry file, 3439 cases of stomach cancer that had telephone number and were diagnosed between years 2001 and 2005 were called to obtain information about their life status. Survival estimates were calculated using the Kaplan-Meier method, and the Survival probability was calculated for the overall cohorts and also for gender and anatomical sites of tumor. Relative ratios (RR) according to demographic and risk variables were calculated by Cox's proportional hazard model.RESULTS: The overall 5-year Survival rate was 12.8%. The likelihood of death was higher in men (RR=1.21; 95% CI: 1.11-1.33) and patients more than 70 years old had worse prognosis rather than those below fifty years old (RR=1.67; 95% CI: 1.46-1.91). The 5-year Survival rate for tumors located in antrum was significantly higher than corpus and cardia (p=0.009). Patients with lymphoma had a significantly higher 5-year Survival rate compared to those with adenocarcinoma (RR=0.46; 95% CI: 0.31-0.66).CONCLUSIONS: The status of stomach cancer, including relative low Survival rate in Iran, indicates the extremely urgent needs for health authorities to adopt measures of cancer prevention that proved effective in other countries.

Background: Although presence of pulmonary metastasis is indicative of disease progression and its untreatable nature, in recent decades, numerous efforts have been made for treatment of these patients by surgical resection of metastatic lesions. The efficacy of this procedure has been variable in various reports and different diseases. This study aimed to evaluate the effect of metastatectomy in Survival rate of patients with pulmonary metastases who underwent metastatectomy in Masih Daneshvari hospital. Materials and Methods: This was a retrospective study and we evaluated medical records of 99 patients suffering pulmonary metastasis who had been referred to our center during 1995-2007; out of which 48 patients who were qualified for metastatectomy underwent this operation. The required qualifications for surgery included: feasibility of resecting all metastatic lesions, tolerance of surgery by the patient, absence of metastatic lesions in organs other than the lungs, and control of primary disease. Information regarding the site of primary lesion and its pathology, time interval between the diagnosis of primary disease and metastasis, surgical morbidity and mortality, form of surgical procedure, type of incision, number of pulmonary metastases and Survival rate of patients was collected. Patients were followed up via clinical visits. In case of insufficient clinical visits, we contacted the patient or his/her family and collected the rewired data. Obtained data were analyzed using SPSS software. To assess the patients' Survival rate after the operation, Kaplan-Meier test was used.Results: Sixty-seven pulmonary metastatectomies were conducted on 48 patients (31 males and 17 females) in the age range of 16-86 years (mean 40 yrs). Twenty-five patients had unilateral and 23 had bilateral metastases. Among patients with bilateral metastases, 7 underwent single-phase metastatectomy while 16 underwent two or multi-phase metastatectomy. Surgical incisions were done through the following approaches: in 60 cases through postero-lateral thoracotomy, in 4 cases through mid-sternotomy and in 3 cases through bilateral anterior-transverse thoracotomy along with sternotomy (clamshell). In 61 cases pulmonary metastatic lesion was removed by wedge resection, in 14 cases by lobectomy and in one case by pneumonectomy. Mean number of resected lesions was 6.7 (range 1 to 59). Postoperative complications occurred in 10 patients (15%) including pneumothorax in 9 cases and chylothorax in one. No morbidity, mortality or life-threatening complications occurred in any of the patients. The mean Survival of patients following metastatectomy was 22 months (range 1 to 128 months) and their 5-year Survival was 24.5% Five patients had 5 years (60 months) or more Survival.Conclusion: Although the under-study population was not homogenous pathologically, it seems that metastatectomy with acceptable morbidity, increases the Survival of patients and in some cases results in their complete recovery.

Introduction: Cardiovascular disease is considered as the most important cause of mortality among men and women throughout the world. This condition causes sudden cardiac arrest in more than half of the cases. To reduce mortality due to this disease, cardiopulmonary resuscitation (CPR) and the determinants of its success are the focus of researchers.Objective: The aim of this study was to determine the Survival rate of CPR and its associated factors in patients with in-hospital cardiac arrest in a teaching medical center in Rasht.Materials and Methods: The present descriptive-analytic cross-sectional study investigated 100 patients undergoing CPR during spring-summer 2014 at Specialized Cardiology Center in Rasht. The instrument of this study was the standard checklist of Utstein-Style that included information on age, gender, cause of cardiac arrest, rhythm, work shift, CPR place, interval of cardiac arrest until arrival of CPR team, interval of cardiac arrest until shock, interval of cardiac arrest until intubation, interval of cardiac arrest until CPR termination, short-term and long-term outcomes of CPR, and brain function status until discharge from the hospital. Data was analyzed using descriptive statistics (mean, standard deviation) and analytic analyses (T-test, Fisher’s exact test, analysis of variance, and logistic regression).Results: A total of 53% of subjects were male and mean age of the patients was 68.6 ± 14.4 years; 30% of patients who underwent CPR had short-term Survival, and 11% were discharged with appropriate brain status with Glasgow Coma Scale (GCS=15). Multiple logistic regression (Backward LR method) revealed that only gender (p=0.008, OR=6.46, CI95%: 1.63-25.5) and electric shock (p=0.03, OR=4.1, CI95%: 1.1-15.14) were statistically significant predictors of short-term Survival.Conclusion: According to the results of this study, time is an important factor in CPR outcome and increasing the Survival rate and timely use of electric shock can be an effective measure in shockable rhythms. Appropriate planning, training staff, and using appropriate facilities, as well as establishment of a primary warning system for calling CPR team in health centers can increase the success rate of CPR.